The effect of analgesic doses of morphine on regional cerebral glucose metabolism in pain-related structures.
نویسندگان
چکیده
The effect of morphine on regional cerebral glucose metabolism was measured in rats using high resolution [14C]2-deoxyglucose autoradiography with concurrent confirmation of morphine-induced analgesia measured by tail-flick latency to noxious heat. Within the limits of resolution of this technique, doses of morphine sufficient to inhibit the tail-flick reflex had no significant effect on glucose metabolism in structures implicated in the modulation of pain.
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ورودعنوان ژورنال:
- Brain research
دوره 368 1 شماره
صفحات -
تاریخ انتشار 1986